FIV: Feline Immunodeficiency Virus

Source: Cornell University College of Veterinary Medicine, http://www.vet.cornell.edu

 

What is Feline Immunodeficiency Virus?

Virologists classify feline immunodeficiency virus (FIV) as a lentivirus (or "slow virus"). FIV is in the same retrovirus family as feline leukemia virus (FeLV), but the viruses differ in many ways including their shape. FIV is elongated, while FeLV is more circular. The two viruses are also quite different genetically, and the proteins that compose them are dissimilar in size and composition. The specific ways in which they cause disease differ, as well.

How common is the infection?

FIV-infected cats are found worldwide, but the prevalence of infection varies greatly. (..) Because biting is the most efficient means of viral transmission, free-roaming, aggressive male cats are the most frequently infected, while cats housed exclusively indoors are much less likely to be infected.

How is FIV spread?

The primary mode of transmission is through bite wounds. Casual, non-aggressive contact does not appear to be an efficient route of spreading FIV; as a result, cats in households with stable social structures where housemates do not fight are at little risk for acquiring FIV infections. On rare occasions infection is transmitted from an infected mother cat to her kittens, usually during passage through the birth canal or when the newborn kittens ingest infected milk. Sexual contact is not a major means of spreading FIV.

What does FIV do to a cat?

Infected cats may appear normal for years. However, infection eventually leads to a state of immune deficiency that hinders the cat's ability to protect itself against other infections. The same bacteria, viruses, protozoa, and fungi that may be found in the everyday environment, where they usually do not affect healthy animals, can cause severe illness in those with weakened immune systems. These secondary infections are responsible for many of the diseases associated with FIV.

What are the signs of disease caused by FIV?

Early in the course of infection, the virus is carried to nearby lymph nodes, where it reproduces in white blood cells known as T-lymphocytes. The virus then spreads to other lymph nodes throughout the body, resulting in a generalized but usually temporary enlargement of the lymph nodes, often accompanied by fever. This stage of infection may pass unnoticed unless the lymph nodes are greatly enlarged. An infected cat's health may deteriorate progressively or be characterized by recurrent illness interspersed with periods of relative health. Sometimes not appearing for years after infection, signs of immunodeficiency can appear anywhere throughout the body.

·         Poor coat condition and persistent fever with a loss of appetite are commonly seen.

·         Inflammation of the gums (gingivitis) and mouth (stomatitis) and chronic or recurrent infections of the skin, urinary bladder, and upper respiratory tract are often present.

·         Persistent diarrhea can also be a problem, as can a variety of eye conditions.

·         Slow but progressive weight loss is common, followed by severe wasting late in the disease process.

·         Various kinds of cancer and blood diseases are much more common in cats infected with FIV, too.

·         In unspayed female cats, abortion of kittens or other reproductive failures have been noted.

·         Some infected cats experience seizures, behavior changes, and other neurological disorders.

How is infection diagnosed?

Antibody tests detect the presence of antibodies in the blood of infected cats.

How can I keep my cat from becoming infected?

The only sure way to protect cats is to prevent their exposure to the virus. Cat bites are the major way infection is transmitted, so keeping cats indoors-and away from potentially infected cats that might bite them-markedly reduces their likelihood of contracting FIV infection. For the safety of the resident cats, only infection-free cats should be adopted into a household with uninfected cats. Vaccines to help protect against FIV infection are now available. However, not all vaccinated cats will be protected by the vaccine, so preventing exposure will remain important, even for vaccinated pets. In addition, vaccination may have an impact on future FIV test results. It is important that you discuss the advantages and disadvantages of vaccination with your veterinarian to help you decide whether FIV vaccines should be administered to your cat.  

How should FIV-infected cats be managed?

·         FIV-infected cats should be confined indoors to prevent spread of FIV infection to other cats in the neighborhood and to reduce their exposure to infectious agents carried by other animals.

·         FIV-infected cats should be spayed or neutered.

·         They should be fed nutritionally complete and balanced diets.

·         Uncooked food, such as raw meat and eggs, and unpasteurized dairy products should not be fed to FIV-infected cats because the risk of food-borne bacterial and parasitic infections is much higher in immunosuppressed cats.

·         Wellness visits for FIV-infected cats should be scheduled with your veterinarian at least every six months. Although a detailed physical examination of all body systems will be performed, your veterinarian will pay special attention to the health of the gums, eyes, skin, and lymph nodes. Your cat's weight will be measured accurately and recorded, because weight loss is often the first sign of deterioration. A complete blood count, serum biochemical analysis, and a urine analysis should be performed annually.

·         Vigilance and close monitoring of the health and behavior of FIV-infected cats is even more important than it is for uninfected cats. Alert your veterinarian to any changes in your cat's health as soon as possible.

·         There is no evidence from controlled scientific studies to show that immunomodulator, alternative, or antiviral medications have any positive benefits on the health or longevity of healthy FIV-infected cats. However, some antiviral therapies have been shown to benefit some FIV-infected cats with seizures or stomatitis.

How long can I expect my FIV-infected cat to live?

It is impossible to accurately predict the life expectancy of a cat infected with FIV. With appropriate care and under ideal conditions, many infected cats will remain in apparent good health for many months or years. If your cat has already had one or more severe illnesses as a result of FIV infection, or if persistent fever and weight loss are present, a much shorter survival time can be expected.

My FIV-infected cat died recently after a long illness. How should I clean my home before bringing in a new cat?

Feline immunodeficiency virus will not survive outside the cat for more than a few hours in most environments. However, FIV-infected cats are frequently infected with other infectious agents that may pose some threat to a newcomer. Thoroughly clean and disinfect or replace food and water dishes, bedding, litter pans, and toys. A dilute solution of household bleach (four ounces of bleach in 1 gallon of water) makes an excellent disinfectant. Vacuum carpets and mop floors with an appropriate cleanser. Any new cats or kittens should be properly vaccinated against other infectious agents before entering the household.

Can I become infected with FIV?

Although FIV is a lentivirus similar to HIV (the human immunodeficiency virus) and causes a disease in cats similar to AIDS (acquired immune deficiency syndrome) in humans, it is a highly species-specific virus that infects only felines.

Why should I have my cat tested?

Early detection will help you maintain the health of your own cat and also allow you to prevent spreading infection to other cats.  

 

ATTENTION: these are only general tips, every treatment is on case by case basis so if your cat has this disease you should consult the vet.